Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 8/20 | 0.47 |
| ▸ | ACE | P12821 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896980 | 1.00 | LPAR1 (0.48) | LPAR1KMT2AMMEACEPPARG | |
| SCHEMBL6897944 | 0.89 | KMT2A (0.61) | LPAR1KMT2AMMEACEPPARG | |
| SCHEMBL6895388 | 0.88 | LPAR1 (0.53) | LPAR1MMEACECPA1ACE2 | |
| SCHEMBL6891317 | 0.88 | LPAR1 (0.53) | LPAR1MMEACECPA1ACE2 | |
| SCHEMBL27538262 | 0.88 | LPAR1 (0.53) | LPAR1MMEACECPA1ACE2 | |
| SCHEMBL6895776 | 0.87 | SRC (0.43) | KMT2ACNR2 | |
| SCHEMBL6898401 | 0.86 | PPARG (0.56) | MMEACEPPARGCPA1ACE2 | |
| SCHEMBL27559954 | 0.86 | PPARG (0.56) | MMEACEPPARGCPA1ACE2 | |
| SCHEMBL6895621 | 0.86 | MME (0.57) | LPAR1MMEACECPA1ACE2 | |
| SCHEMBL6896715 | 0.85 | ACE (0.54) | LPAR1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1299344-A | Novel urea derivatives | SANTEN PHARCEUMATICAL CO LTD (JP) | 2001-06-13 | — | — | CN | disclosed |