Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.40 |
| ▸ | FNTB | P49356 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681603 | 1.00 | FNTA (0.40) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL7679318 | 0.90 | HPGD (0.39) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL7679322 | 0.90 | HPGD (0.39) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL11042524 | 0.89 | FNTA (0.39) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL11041963 | 0.89 | FNTA (0.39) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL11045633 | 0.89 | FNTA (0.39) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL11043412 | 0.89 | FNTA (0.39) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL10565035 | 0.88 | KMT2A (0.45) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL10566716 | 0.88 | KMT2A (0.45) | FNTAFNTBALDH1A1ALOX15NFE2L2 | |
| SCHEMBL10570887 | 0.88 | KMT2A (0.45) | FNTAFNTBALDH1A1ALOX15NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |