Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CASP2 | P42575 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14957804 | 0.86 | TDP1 (0.54) | TDP1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL14633638 | 0.86 | TDP1 (0.54) | TDP1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL48440 | 0.82 | — | — | |
| SCHEMBL30161 | 0.82 | — | — | |
| SCHEMBL10353078 | 0.82 | TDP1 (0.62) | TDP1CYP2C19CYP2C9TSHRALDH1A1 | |
| SCHEMBL12501988 | 0.82 | CA12 (0.50) | TDP1CYP2C19CYP2C9TSHRALDH1A1 | |
| SCHEMBL27121 | 0.82 | — | — | |
| SCHEMBL680485 | 0.81 | CHRM2 (0.54) | TDP1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL28179107 | 0.80 | TDP1 (0.77) | TDP1CYP2C19CYP2C9TSHRALDH1A1 | |
| SCHEMBL380653 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441174-B1 | REACTING PERYLENE-3,4,9,10-TETRACARBOXIMIDE OR DERIVATIVES WITH FORMALDEHYDE TO FORM BIS(HYDROXYMETHYL)PERYLENE-3,4,9,10-TETRACARBOXIMIDE, WHICH FURTHER REACTS WITH A PRECURSOR OF ORGANIC REDICALS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-08-27 | — | — | US | disclosed |