Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 20/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045824 | 0.99 | LSS (0.80) | LSSMEN1KMT2A | |
| SCHEMBL6446150 | 0.96 | LSS (0.75) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL5038630 | 0.92 | LSS (0.70) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL5038627 | 0.92 | LSS (0.70) | LSSMEN1KMT2A | |
| SCHEMBL17358778 | 0.90 | LSS (1.00) | LSSMEN1KMT2A | |
| SCHEMBL5043394 | 0.89 | LSS (0.80) | LSSMEN1KMT2A | |
| SCHEMBL6446420 | 0.87 | LSS (0.62) | LSSMEN1KMT2A | |
| SCHEMBL7687746 | 0.87 | LSS (0.62) | LSSMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7687496 | 0.86 | LSS (0.61) | LSSMEN1KMT2A | |
| SCHEMBL4805100 | 0.82 | LSS (0.58) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | claimed |
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |