Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.79 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.79 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.79 |
| ▸ | PDE3B | Q13370 | 13/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.78 |
| ▸ | PDE5A | O76074 | 8/20 | 0.78 |
| ▸ | PDE1A | P54750 | 8/20 | 0.78 |
| ▸ | PDE1B | Q01064 | 8/20 | 0.78 |
| ▸ | PDE1C | Q14123 | 8/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607953 | 0.89 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7160159 | 0.89 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL6307929 | 0.88 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7673788 | 0.86 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7491632 | 0.86 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7491635 | 0.86 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7811813 | 0.85 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7675806 | 0.85 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7680709 | 0.85 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7495374 | 0.85 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365585-B1 | USED AS ANTI-INFLAMMATORIES, ANTI-ALLERGICS, BRONCHODILATORS OR ANTI-ASTHMATICS AND ARE DEVOID OF DIGESTIVE OR CARDIAC SIDE-EFFECTS | WARNER-LAMBERT COMPANY | 2002-04-02 | — | — | US | disclosed |