Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682870 | 1.00 | TACR1 (0.63) | TACR1TACR3 | |
| SCHEMBL7690899 | 1.00 | TACR1 (0.63) | TACR1TACR3 | |
| SCHEMBL7682748 | 0.91 | TACR1 (0.64) | TACR1TACR3 | |
| SCHEMBL7688252 | 0.91 | TACR1 (0.64) | TACR1TACR3 | |
| SCHEMBL7682751 | 0.91 | TACR1 (0.64) | TACR1TACR3 | |
| SCHEMBL7862639 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8925793 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8923727 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8923736 | 0.89 | TACR1 (0.71) | TACR1TACR3 | |
| SCHEMBL8502429 | 0.89 | TACR1 (0.71) | TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346540-B1 | SUBSTANCE P ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM, PSYCHOLOGICAL AND BRAIN DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-02-12 | — | — | US | disclosed |
| EP-0855999-B1 | 1-(1,2-DISUBSTITUTED PIPERIDINYL)-4-SUBSTITUTED PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2001-10-04 | — | — | EP | disclosed |
| US-6169097-B1 | 1-(1,2-Disubstituted piperidinyl)-4-substituted piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-01-02 | — | — | US | disclosed |