Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542044 | 0.90 | EDNRA (0.56) | EDNRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6541202 | 0.87 | EDNRA (0.51) | EDNRAMEN1KMT2AGABRA1GABRB2 | |
| SCHEMBL6542540 | 0.87 | EDNRA (0.49) | EDNRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6542570 | 0.86 | EDNRA (0.51) | EDNRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6542491 | 0.85 | EDNRA (0.51) | EDNRAMEN1KMT2AGABRA1GABRB2 | |
| SCHEMBL6541268 | 0.85 | EDNRA (0.48) | EDNRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7252735 | 0.84 | EDNRA (0.50) | EDNRAMAPTALDH1A1L3MBTL1TP53 | |
| SCHEMBL6542548 | 0.84 | EDNRA (0.47) | EDNRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6542591 | 0.83 | EDNRA (0.66) | EDNRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6542667 | 0.83 | EDNRA (0.47) | EDNRAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440962-B2 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS | WARNER-LAMBERT COMPANY | 2002-08-27 | — | — | US | disclosed |