Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.64 |
| ▸ | F2 | P00734 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448368 | 1.00 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7448372 | 1.00 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7451947 | 0.85 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7681967 | 0.85 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7451943 | 0.85 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7449244 | 0.83 | F10 (1.00) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7690239 | 0.81 | F10 (0.88) | F10PRSS1F2KCNH2 | |
| SCHEMBL7455481 | 0.81 | F10 (1.00) | F10PRSS1F2KCNH2 | |
| SCHEMBL7683937 | 0.81 | F10 (1.00) | F10PRSS1F2KCNH2 | |
| SCHEMBL7455475 | 0.81 | F10 (1.00) | F10PRSS1F2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |