SCHEMBL7684437

SCHEMBL7684437

OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(OCc2ccccc2)c1)C(F)(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045963 0.93 CETP (1.00) CETP
SCHEMBL993675 0.93 CETP (1.00) CETP
SCHEMBL5178604 0.92 CETP (0.85) CETP
SCHEMBL5180495 0.92 CETP (0.84) CETP
SCHEMBL993798 0.91 CETP (0.84) CETP
SCHEMBL7660768 0.91 CETP (0.85) CETP
SCHEMBL992323 0.91 CETP (0.84) CETP
SCHEMBL994110 0.90 CETP (0.82) CETP
SCHEMBL993885 0.90 CETP (1.00) CETP
SCHEMBL992925 0.90 CETP (1.00) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6451830-B1 Use of substituted N,N-disubstituted non-fused heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity G.D. SEARLE & CO. 2002-09-17 US disclosed