Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280651 | 0.84 | CYP1A2 (0.52) | CYP1A2TDP1KDM4ESMN1; SMN2PIK3CD | |
| SCHEMBL4615811 | 0.83 | — | — | |
| SCHEMBL860793 | 0.77 | CYP1A2 (0.77) | CYP1A2TDP1KDM4ESMN1; SMN2PIK3CD | |
| SCHEMBL14407779 | 0.77 | CYP1A2 (0.77) | CYP1A2TDP1KDM4ESMN1; SMN2PIK3CD | |
| SCHEMBL37407 | 0.77 | — | — | |
| SCHEMBL9129433 | 0.76 | CA12 (0.61) | CYP1A2TDP1SMN1; SMN2KMT2ACA12 | |
| SCHEMBL18987792 | 0.75 | FASN (0.44) | SMN1; SMN2KMT2ACA12CA2CA9 | |
| SCHEMBL14590778 | 0.74 | HTT (0.65) | SMN1; SMN2KMT2AMAPT | |
| SCHEMBL8018069 | 0.73 | CYP2D6 (0.53) | SMN1; SMN2KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL7972607 | 0.72 | CYP1A2 (0.41) | CYP1A2TDP1KDM4ESMN1; SMN2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355800-B1 | REACTING 4-ACYL-1-PIPERAZINECARBAMIC ACID WITH ACID OR ITS REACTIVE DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-1043320-A1 | NEW PROCESS FOR PRODUCING AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-11 | — | — | EP | disclosed |