SCHEMBL7684623

SCHEMBL7684623

CCCCCCCCCCCCCCC(C)c1cc(C)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.43
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
CHRM1 P11229 3/20 0.43
LMNA P02545 2/20 0.43
ADRA1A P35348 2/20 0.43
CHRM2 P08172 2/20 0.43
CHRM5 P08912 2/20 0.43
CHRM3 P20309 2/20 0.43
HRH1 P35367 2/20 0.43
ESR1 P03372 1/20 0.43
CHRM4 P08173 1/20 0.43
MAPT P10636 1/20 0.43
KCNE1 P15382 1/20 0.43
PTGS1 P23219 1/20 0.43
HRH2 P25021 1/20 0.43
HTR2A P28223 1/20 0.43
SLC6A4 P31645 1/20 0.43
OPRK1 P41145 1/20 0.43
KCNQ1 P51787 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23406316 1.00 SRC (0.43) SRCCNR1CNR2CHRM1LMNA
SCHEMBL3656115 1.00 SRC (0.43) SRCCNR1CNR2CHRM1LMNA
SCHEMBL10475045 1.00 SRC (0.43) SRCCNR1CNR2CHRM1LMNA
SCHEMBL9500852 1.00 SRC (0.43) SRCCNR1CNR2CHRM1LMNA
SCHEMBL27315241 1.00 SRC (0.43) SRCCNR1CNR2CHRM1LMNA
SCHEMBL11775212 0.93 SRC (0.45) SRCCNR1CNR2CHRM1LMNA
SCHEMBL30893076 0.87 SRC (0.57) SRCCNR1CNR2CHRM1LMNA
SCHEMBL11778568 0.86 SRC (0.47) SRCCNR1CNR2CHRM1LMNA
Potassium SCHEMBL29477981 0.86 SRC (0.56) SRCCNR1CNR2CHRM1LMNA
SCHEMBL29477990 0.86 SRC (0.56) SRCCNR1CNR2CHRM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6359148-B1 FOR POLYMER, LUBRICANTS; HEAT, OXIDATION RESISTANCE, PHOTOSTABILITY NESVADBA PETER (CH) 2002-03-19 US disclosed
US-6346630-B1 3-Arylbenzofuranones as stabilizers CIBA SPECIALTY CHEMICALS CORPORATION 2002-02-12 US disclosed
EP-0648765-B1 Process for the production of 3-arylbenzofuranones CIBA SC HOLDING AG (CH) 2000-07-12 EP disclosed
CN-1052230-C Benzofuran-2-ones as stabilisers CIBA GEIGY AG (CH) 2000-05-10 CN disclosed
EP-0644190-B1 Benzofuran-2-ones as stabilizers CIBA GEIGY AG (CH) 1999-03-17 EP disclosed
US-5814692-A PROTECTING POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-29 US disclosed
US-5807505-A HEAT AND OXIDATION RESISTANCE, PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
US-5773631-A PROTECTION OF POLYMERS AND LUBRICANTS AGAINST THERMAL, OXIDATIVE OR LIGHT INDUCED DEGRDATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-30 US disclosed
US-5693829-A PROTECT AGAINST THERMAL, OXIDATIVE OR LIGHT-INDUCED DEGRADATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-12-02 US disclosed
US-5614572-A Benzofuran-2-ones as stabilizers CIBA-GEIGY CORPORATION (US) 1997-03-25 US disclosed
US-5607624-A Process for the preparation of 3-arylbenzofuranones CIBA-GEIGY CORPORATION (US) 1997-03-04 US disclosed
US-5516920-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0644190-A1 Benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1995-03-22 EP disclosed