SCHEMBL7684683

SCHEMBL7684683

CC(=COOC(C)(C)c1ccccc1)C(=O)OC(C)(C)OC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 3/20 0.37
ALOX15 P16050 1/20 0.37
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNN4 O15554 1/20 0.31
HTT P42858 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
HDAC9 Q9UKV0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9336201 0.85 MAPK1 (0.46) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL7692610 0.80 MAPK1 (0.41) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL8762563 0.79
SCHEMBL8524785 0.78 MAPK1 (0.42) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL7692281 0.78 MAPK1 (0.44) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL10497538 0.77 MAPK1 (0.38) MAPK1ALDH1A1ALOX15TSHRMAPT
SCHEMBL7691676 0.77 MAPK1 (0.38) MAPK1ALDH1A1ALOX15
SCHEMBL7692278 0.77 MAPK1 (0.43) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
Propane SCHEMBL10713290 0.76 MAPK1 (0.37) MAPK1ALDH1A1ALOX15CYP2C19HIF1A
SCHEMBL7691703 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107531978-B Methacrylic resin composition 株式会社可乐丽 2020-11-03 CN disclosed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-6335401-B1 ADHESION PRIMER ATOFINA (FR) 2002-01-01 US disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0608856-B1 Graft precursor and process for producing grafted aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1997-07-09 EP disclosed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP disclosed
EP-0435340-B1 Thermoplastic resin compositions NIPPON PETROCHEMICALS CO LTD (JP) 1996-05-01 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438108-A Melt-kneading a mixture of aromatic polycarbonate resin and vinylic copolymer containing active oxygen; optical distortion reduction MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-08-01 US disclosed
EP-0368295-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1990-05-16 EP disclosed
US-4923956-A Containing free radical polymerizable organic peroxide NIPPON OIL AND FATS CO., LTD. (JP) 1990-05-08 US disclosed
EP-0361400-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-04-04 EP disclosed
EP-0338303-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-10-25 EP disclosed
EP-0314188-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0307802-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-22 EP disclosed
EP-0304039-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304041-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304040-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0295706-A2 Thermoplastic resin composition and method for preparing the same Nippon Petrochemicals Co., Ltd. (JP) 1988-12-21 EP disclosed