Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 6/20 | 0.40 |
| ▸ | FNTB | P49356 | 6/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676544 | 0.85 | FNTA (0.43) | HDAC1NR1H2NR1H3FNTAFNTB | |
| SCHEMBL6634998 | 0.80 | FNTA (0.61) | NR1H2NR1H3FNTAFNTB | |
| SCHEMBL7685900 | 0.80 | FNTA (0.61) | NR1H2NR1H3FNTAFNTB | |
| SCHEMBL6680604 | 0.79 | FNTA (0.41) | HDAC1NR1H2NR1H3FNTAFNTB | |
| SCHEMBL6615703 | 0.78 | FNTA (0.42) | HDAC1NR1H2NR1H3FNTAFNTB | |
| SCHEMBL6632164 | 0.77 | NPC1 (0.39) | HDAC1NR1H2NR1H3FNTAFNTB | |
| SCHEMBL6633491 | 0.75 | USP30 (0.43) | HDAC1NR1H2NR1H3FNTAFNTB | |
| SCHEMBL3502173 | 0.75 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL6637954 | 0.72 | FNTA (0.46) | FNTAFNTBSIRT1SIRT2 | |
| SCHEMBL3499277 | 0.71 | FNTA (0.54) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |