Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778849 | 0.91 | PDE5A (0.68) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6726800 | 0.88 | PDE5A (0.70) | PDE5APDE2A | |
| SCHEMBL7682771 | 0.86 | PDE5A (0.65) | PDE5APDE2A | |
| SCHEMBL6774772 | 0.85 | PDE5A (0.53) | PDE5APDE2A | |
| SCHEMBL7689109 | 0.81 | PDE5A (0.54) | PDE5APDE2A | |
| SCHEMBL7077106 | 0.81 | PDE5A (0.58) | PDE5APDE2A | |
| SCHEMBL6773862 | 0.80 | PDE5A (0.60) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6718444 | 0.80 | PDE5A (0.81) | PDE5APDE2A | |
| SCHEMBL6780463 | 0.79 | PDE5A (0.86) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6779091 | 0.79 | PDE5A (0.63) | PDE5APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498159-B1 | SUCH AS 4-((3-CHLORO-4-METHOXYBENZYL)AMINO)-1-((4-HYDROXY-4 -HYDROXYMETHYL)PIPERIDINO)-6-PHTHALAZINE CARBONITRILE | EISAI CO., LTD. (JP) | 2002-12-24 | — | — | US | claimed |
| EP-1057819-A1 | PHTHALAZINE DERIVATIVES AND REMEDIES FOR ERECTILE DYSFUNCTION | Eisai Co., Ltd. (JP) | 2000-12-06 | — | — | EP | claimed |