Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594678 | 0.92 | PDE5A (1.00) | PDE5A | |
| SCHEMBL27510101 | 0.88 | PDE5A (0.81) | PDE5A | |
| SCHEMBL27491546 | 0.88 | PDE5A (0.81) | PDE5A | |
| SCHEMBL27563557 | 0.88 | PDE5A (0.81) | PDE5A | |
| SCHEMBL7914743 | 0.87 | PDE5A (1.00) | PDE5A | |
| SCHEMBL7686667 | 0.87 | PDE5A (0.80) | PDE5A | |
| SCHEMBL7678377 | 0.87 | PDE5A (0.76) | PDE5A | |
| SCHEMBL7991813 | 0.86 | PDE5A (1.00) | PDE5A | |
| SCHEMBL7688658 | 0.84 | PDE5A (0.75) | PDE5A | |
| SCHEMBL7983725 | 0.83 | PDE5A (1.00) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1210265-C | Phthalazine derivatives and remedies for erectile dysfunction | EISAI CO LTD (JP) | 2005-07-13 | — | — | CN | disclosed |
| US-6498159-B1 | SUCH AS 4-((3-CHLORO-4-METHOXYBENZYL)AMINO)-1-((4-HYDROXY-4 -HYDROXYMETHYL)PIPERIDINO)-6-PHTHALAZINE CARBONITRILE | EISAI CO., LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| CN-1275124-A | Phthalazine derivatives and remedies for erectile dysfunction | EISAI CO LTD (JP) | 2000-11-29 | — | — | CN | disclosed |