Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617796 | 0.90 | SPHK1 (0.41) | SPHK1BRD4HSD11B2MAOB | |
| SCHEMBL3617792 | 0.90 | SPHK1 (0.41) | SPHK1BRD4HSD11B2MAOB | |
| SCHEMBL502794 | 0.90 | SPHK1 (0.41) | SPHK1BRD4HSD11B2DDB1CRBN | |
| SCHEMBL502795 | 0.90 | SPHK1 (0.41) | SPHK1BRD4HSD11B2DDB1CRBN | |
| SCHEMBL14350826 | 0.90 | SPHK1 (0.42) | SPHK1BRD4HSD11B2KDM4E | |
| SCHEMBL14338696 | 0.90 | SPHK1 (0.42) | SPHK1BRD4HSD11B2KDM4E | |
| SCHEMBL6924329 | 0.90 | SPHK1 (0.42) | SPHK1BRD4HSD11B2KDM4E | |
| SCHEMBL1760155 | 0.89 | BRD4 (0.41) | SPHK1BRD4HSD11B2KDM4E | |
| SCHEMBL1760152 | 0.89 | BRD4 (0.41) | SPHK1BRD4HSD11B2KDM4E | |
| SCHEMBL2290590 | 0.88 | SPHK1 (0.43) | SPHK1BRD4HSD11B2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |