Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 13/20 | 0.47 |
| ▸ | F2 | P00734 | 7/20 | 0.47 |
| ▸ | F7 | P08709 | 7/20 | 0.47 |
| ▸ | F10 | P00742 | 6/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656580 | 0.90 | F3 (0.58) | F3F2F7F10PRSS1 | |
| SCHEMBL7689356 | 0.88 | F3 (0.63) | F3F2F7F10PRSS1 | |
| SCHEMBL7651999 | 0.83 | F7 (0.51) | F3F2F7F10PRSS1 | |
| SCHEMBL7661746 | 0.83 | F2 (0.59) | F3F2F7F10PRSS1 | |
| SCHEMBL7653678 | 0.82 | F3 (0.62) | F3F2F7F10PRSS1 | |
| SCHEMBL7659099 | 0.82 | F7 (0.49) | F3F2F7F10PRSS1 | |
| SCHEMBL7664274 | 0.81 | F3 (0.60) | F3F2F7F10PRSS1 | |
| SCHEMBL7654080 | 0.81 | F3 (0.60) | F3F2F7F10PRSS1 | |
| SCHEMBL7664223 | 0.81 | F3 (0.53) | F3F2F7F10PRSS1 | |
| SCHEMBL7659312 | 0.80 | F7 (0.60) | F3F2F7F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |