Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7685404 | 0.94 | LSS (0.61) | LSSMEN1KMT2APARP10PARP15 | |
| SCHEMBL7687793 | 0.86 | LSS (0.61) | LSSMEN1KMT2APARP10PARP15 | |
| Hydrochloric Acid SCHEMBL7687465 | 0.85 | LSS (0.60) | LSSMEN1KMT2APARP10PARP15 | |
| SCHEMBL21123272 | 0.85 | LSS (0.64) | LSSMEN1KMT2APARP10PARP15 | |
| SCHEMBL7683275 | 0.82 | LSS (0.45) | LSSFFAR4 | |
| SCHEMBL7681910 | 0.81 | LSS (0.65) | LSSMEN1KMT2APARP10PARP15 | |
| Fumaric Acid SCHEMBL7687488 | 0.81 | LSS (0.56) | LSSPARP10PARP15FFAR4 | |
| SCHEMBL17358774 | 0.80 | LSS (1.00) | LSSMEN1KMT2APARP10PARP15 | |
| SCHEMBL7688275 | 0.80 | LSS (1.00) | LSSMEN1KMT2APARP10PARP15 | |
| Fumaric Acid SCHEMBL7686200 | 0.77 | LSS (0.42) | LSSFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | claimed |
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | claimed |
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |