SCHEMBL7689039

SCHEMBL7689039

c1ccc(C2COC(c3ccccc3C3=NC(c4ccccc4)CO3)=N2)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.61
TAAR1 Q96RJ0 3/20 0.59
ALDH1A1 P00352 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
POLB P06746 1/20 0.56
HTT P42858 2/20 0.48
LMNA P02545 1/20 0.48
TSHR P16473 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NOS3 P29474 1/20 0.42
INPP5D Q92835 1/20 0.42
HSD17B10 Q99714 1/20 0.41
CYP19A1 P11511 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29708126 1.00 MAPT (0.61) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL19367694 0.90 MAPT (0.67) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL28682353 0.90 TAAR1 (0.62) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL28665805 0.90 TAAR1 (0.62) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL28665807 0.90 TAAR1 (0.62) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL28695196 0.88 MAPT (0.54) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL28695201 0.88 MAPT (0.54) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL22745044 0.87 MAPT (0.52) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL28676137 0.85 MAPT (0.51) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1
SCHEMBL1149438 0.85 NPC1 (0.71) MAPTTAAR1ALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2660295-B1 Metal article coated with a composition comprising olefinic double bonds EVONIK OPERATIONS GMBH (DE) 2022-06-08 EP disclosed
EP-2783835-B1 METHOD FOR MANUFACTURING A TUBE CLAD WITH AN INNER LINER EVONIK DEGUSSA GMBH (DE) 2019-09-11 EP disclosed
US-10113671-B2 Process for the production of a pipe lined with an inliner EVONIK DEGUSSA GMBH (DE) 2018-10-30 US disclosed
US-9556358-B2 Coated metallic article EVONIK DEGUSSA GMBH (DE) 2017-01-31 US disclosed
US-20140291032-A1 PROCESS FOR THE PRODUCTION OF A PIPE LINED WITH AN INLINER EVONIK INDUSTRIES AG (DE) 2014-10-02 US disclosed
EP-2783835-A1 Method for manufacturing a tube clad with an inner liner Evonik Industries AG (DE) 2014-10-01 EP disclosed
EP-2660295-A1 Metal article coated with a composition comprising olefinic double bonds Evonik Industries AG (DE) 2013-11-06 EP disclosed
US-20130287981-A1 COATED METALLIC ARTICLE EVONIK INDUSTRIES AG (DE) 2013-10-31 US disclosed
US-6500554-B2 SURFACE TREATMENT OF METAL BY APPLYING FUNCTIONALIZED ALKOXYSILANE; EXTRUDING MELT OF POLYAMIDE MOLDING; DRYING; CORROSION RESISTANCE; PROTECTIVE COATINGS DEGUSSA AG (DE) 2002-12-31 US disclosed
US-20010023537-A1 SURFACE TREATMENT OF METAL BY APPLYING FUNCTIONALIZED ALKOXYSILANE; EXTRUDING MELT OF POLYAMIDE MOLDING; DRYING; CORROSION RESISTANCE; PROTECTIVE COATINGS DEGUSSA-HUELS (DE) 2001-09-27 US disclosed
EP-1130066-A1 Method for producing an extrusion coated metal object Degussa AG (DE) 2001-09-05 EP disclosed