Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.70 |
| ▸ | TP53 | P04637 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.59 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22080090 | 0.77 | TP53 (0.66) | SMN1; SMN2TP53MAPTCYP1A2CYP3A4 | |
| SCHEMBL7951612 | 0.75 | NPY1R (0.71) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL7690343 | 0.75 | NPY1R (0.71) | SMN1; SMN2TP53MAPTKMT2ANPY1R | |
| SCHEMBL7689046 | 0.74 | CYP1A2 (0.66) | SMN1; SMN2TP53MAPTPOLBCYP1A2 | |
| SCHEMBL20083834 | 0.72 | MAPT (0.69) | SMN1; SMN2TP53MAPTMEN1KMT2A | |
| SCHEMBL15085842 | 0.72 | NPY1R (0.69) | SMN1; SMN2TP53MAPTCYP1A2CYP3A4 | |
| SCHEMBL7689384 | 0.71 | NPY1R (0.68) | TP53NPY1R | |
| SCHEMBL7684732 | 0.71 | NPY1R (1.00) | SMN1; SMN2TP53MAPTCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL30282000 | 0.70 | HIF1A (0.64) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL29205453 | 0.70 | HIF1A (0.64) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007071-A1 | Benzimidzolyl neuropeptide Y receptor antagonists | BRITTON THOMAS CHARLES (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007071-A1 | Benzimidzolyl neuropeptide Y receptor antagonists | NPY1R, NPY2R, NPY5R | SMN1; SMN2 2698/4885TP53 4432/4885MAPT 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.