Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696205 | 0.89 | HSP90AA1 (0.39) | NR1H4KDM6BKDM4ETHRATHRB | |
| SCHEMBL8074200 | 0.78 | NPC1 (0.38) | HDAC8MDM2NPC1THRATHRB | |
| SCHEMBL416327 | 0.75 | NR1H4 (0.37) | NR1H4ALDH1A1 | |
| SCHEMBL3968291 | 0.73 | NR1H4 (0.38) | NR1H4ALDH1A1MAPK1 | |
| SCHEMBL3651085 | 0.72 | FFAR4 (0.35) | HDAC8NPC1TBXA2R | |
| SCHEMBL4815914 | 0.71 | PPARG (0.34) | KDM4EMCL1PPARA | |
| SCHEMBL9845237 | 0.70 | KDM6B (0.45) | KDM6BKDM4ETBXA2RTHRATHRB | |
| SCHEMBL30891619 | 0.70 | KDM6B (0.45) | KDM6BKDM4EALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL19379230 | 0.69 | NR1H4 (0.38) | NR1H4KDM4EALDH1A1 | |
| SCHEMBL7892985 | 0.69 | SLC7A5 (0.67) | NR1H4KDM4ETHRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002079173-A1 | BENZOTRIAZOLES AND THEIR USE AS UV LIGHT STABILISERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | disclosed |