SCHEMBL7690178

SCHEMBL7690178

CNc1cc(Oc2cccc(C(F)(F)F)c2)nc(C(=O)Nc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
GAA P10253 3/20 0.56
RAB9A P51151 1/20 0.51
MAPK1 P28482 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
P2RY1 P47900 1/20 0.50
LMNA P02545 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
KDR P35968 5/20 0.49
MAPK14 Q16539 3/20 0.49
TNNI3K Q59H18 3/20 0.49
LOX P28300 2/20 0.49
LOXL2 Q9Y4K0 2/20 0.49
BRAF P15056 2/20 0.49
NTRK1 P04629 1/20 0.49
TLR8 Q9NR97 1/20 0.48
TLR7 Q9NYK1 1/20 0.48
KDM4E B2RXH2 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052802 0.91 MAPT (0.58) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL20894934 0.88 GAA (0.57) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL7113284 0.88 MAPT (0.62) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL7612444 0.87 MAPT (0.67) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL7051149 0.87 MAPT (0.53) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL7054659 0.87 MAPT (0.53) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL7050555 0.86 MAPT (0.57) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL8721207 0.84 NTRK1 (0.63) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL7054903 0.82 KCNH2 (0.51) MAPTGAARAB9AMAPK1L3MBTL1
SCHEMBL7953536 0.81 MAPT (0.69) MAPTGAARAB9AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6339045-B1 CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-01-15 US disclosed
EP-0882715-A1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-09 EP disclosed