Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697529 | 1.00 | KDM4E (0.49) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL13557891 | 0.87 | KDM4E (0.56) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL11354803 | 0.86 | KDM4E (0.49) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL29108644 | 0.83 | KDM4E (0.46) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL7260873 | 0.82 | KDM4E (0.61) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL21843009 | 0.80 | KDM4E (0.53) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL95926 | 0.80 | KDM4E (0.56) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL7405277 | 0.79 | KDM4E (0.45) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL11386587 | 0.79 | KDM4E (0.45) | KDM4EPOLBTSHRCA1ALDH1A1 | |
| SCHEMBL7405279 | 0.79 | KDM4E (0.45) | KDM4EPOLBTSHRCA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081441-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRROLIDINE NEURAMINIDASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-10-17 | — | — | WO | claimed |