SCHEMBL769129

SCHEMBL769129

Cc1c(O)cc(O)cc1C=O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 8/20 0.46
TYR P14679 2/20 0.42
TRIM24 O15164 2/20 0.42
TRIM33 Q9UPN9 2/20 0.42
ACHE P22303 2/20 0.39
CYP3A4 P08684 3/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28123711 0.88 ERN1 (0.52) ERN1TYRTRIM24TRIM33ESR1
SCHEMBL3469126 0.82 ERN1 (0.46) ERN1TYRTRIM24TRIM33ACHE
SCHEMBL1981683 0.82 ERN1 (0.64) ERN1TYRTRIM24TRIM33ACHE
SCHEMBL12311286 0.79 CYP3A4 (0.63) ERN1TYRTRIM24TRIM33CYP3A4
SCHEMBL13447874 0.78 ERN1 (0.53) ERN1TYRTRIM24TRIM33ACHE
SCHEMBL12957472 0.78 ERN1 (0.53) ERN1TYRTRIM24TRIM33ACHE
SCHEMBL69626 0.77 ESR1 (0.44) ACHECYP3A4MEN1HPGDKMT2A
SCHEMBL29459679 0.76 ERN1 (0.50) ERN1TYRTRIM24TRIM33ESR1
SCHEMBL1003422 0.76 ERN1 (0.50) ERN1TYRTRIM24TRIM33ESR1
SCHEMBL10118325 0.74 ERN1 (0.42) ERN1TYRTRIM24TRIM33CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0961615-A4 ANTIMICROBIAL AGENT DORLIN PHARM INC (US) 2002-09-11 EP claimed
EP-0961615-A1 ANTIMICROBIAL AGENT Dorlin Pharmaceuticals, Inc. (US) 1999-12-08 EP claimed
US-5910509-A ADMINISTERING SUBSTITUTED ISOCHROMENE DERIVATIVE; FUNGICIDES DORLIN PHARMACEUTICALS, INC. 1999-06-08 US claimed
US-5859027-A Antimicrobial agent CHEKTEC CORPORATION (US) 1999-01-12 US claimed
WO-1998037890-A1 ANTIMICROBIAL AGENT DORLIN PHARMACEUTICALS, INC. (US) 1998-09-03 WO claimed
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 US disclosed
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 US disclosed
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF UNIV MICHIGAN TECH (US) 2017-01-19 US disclosed
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF UNIV MICHIGAN TECH (US) 2017-01-19 US disclosed
US-9412949-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2016-08-09 US disclosed
US-9412949-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2016-08-09 US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 US disclosed
EP-0961615-A4 ANTIMICROBIAL AGENT DORLIN PHARM INC (US) 2002-09-11 EP disclosed
EP-0961615-A1 ANTIMICROBIAL AGENT Dorlin Pharmaceuticals, Inc. (US) 1999-12-08 EP disclosed
US-5910509-A ADMINISTERING SUBSTITUTED ISOCHROMENE DERIVATIVE; FUNGICIDES DORLIN PHARMACEUTICALS, INC. 1999-06-08 US disclosed
US-5859027-A Antimicrobial agent CHEKTEC CORPORATION (US) 1999-01-12 US disclosed
WO-1998037891-A1 ANTIMICROBIAL AGENT FOR AGRICULTURE DORLIN PHARMACEUTICALS, INC. (US) 1998-09-03 WO disclosed
WO-1998037890-A1 ANTIMICROBIAL AGENT DORLIN PHARMACEUTICALS, INC. (US) 1998-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 ERN1 2316/4885TYR 2195/4885TRIM24 819/4885
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 ERN1 2316/4885TYR 2195/4885TRIM24 819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.