Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705783 | 1.00 | TSHR (0.39) | TSHRTDP1SMN1; SMN2CYP3A4PKM | |
| SCHEMBL7218448 | 0.93 | TSHR (0.39) | TSHRTDP1SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL9282144 | 0.93 | TSHR (0.39) | TSHRTDP1SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL11359855 | 0.80 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL11725731 | 0.77 | MGAM (0.39) | TSHRCYP3A4PKM | |
| SCHEMBL3937564 | 0.77 | MGAM (0.39) | TSHRCYP3A4PKM | |
| SCHEMBL452542 | 0.77 | TSHR (0.39) | TSHRTDP1SMN1; SMN2CYP3A4PKM | |
| Bicarbonate SCHEMBL28099196 | 0.75 | TSHR (0.40) | TSHRTDP1SMN1; SMN2CYP3A4PKM | |
| SCHEMBL194466 | 0.74 | TSHR (0.42) | TSHRTDP1SMN1; SMN2CYP3A4PKM | |
| SCHEMBL7866089 | 0.74 | TSHR (0.42) | TSHRTDP1SMN1; SMN2CYP3A4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500548-B2 | POWDER COATING | DEGUSSA AG (DE) | 2002-12-31 | — | — | US | disclosed |
| US-6491986-B2 | PROTECTIVE COATINGS | DEGUSSA AG (DE) | 2002-12-10 | — | — | US | disclosed |
| US-6306967-B1 | POLYURETHANE WITH OXAZOLINE AND ISOCYANURATE GROUPS | Degussa-Hüls Aktiengesellschaft (DE) | 2001-10-23 | — | — | US | disclosed |
| US-20010024696-A1 | Transparent or pigmented powder coating materials with crosslinkers comprising hydroxyalkylamides and polyisocyanates containing uretdione groups | DEGUSSA-HULS AKTIENGESELLSCHAFT (DE) | 2001-09-27 | — | — | US | disclosed |
| US-20010021748-A1 | Transparent or pigmented powder coating materials with crosslinkers comprising hydroxyalkylamides and blocked nonaromatic polyisocyanates | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2001-09-13 | — | — | US | disclosed |