Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294299 | 0.82 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL294301 | 0.82 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL366950 | 0.82 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16188381 | 0.82 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16198890 | 0.82 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7693288 | 0.76 | CYP2D6 (0.43) | CYP2D6MC4ROPRM1OPRD1OPRK1 | |
| SCHEMBL16269690 | 0.71 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL294258 | 0.71 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL294259 | 0.71 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11963748 | 0.71 | CYP2D6 (0.46) | CYP2D6CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012184-A1 | PROCESS FOR PREPARING ALPHA-AMINO ACIDS AND THEIR DERIVATIVES INCLUDING PHENYLALANINE AND HOMOPHENYLALANINE AND THEIR INTERMEDIATES | CHEMBIONEX CO., LTD. (KR) | 2002-02-14 | — | — | WO | disclosed |