SCHEMBL769251

SCHEMBL769251

CC=Cc1ccc(-c2cccs2)s1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.61
ALDH1A1 P00352 7/20 0.49
KDM4E B2RXH2 5/20 0.49
GAA P10253 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
HSD17B10 Q99714 3/20 0.49
GLA P06280 2/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 2/20 0.49
POLB P06746 2/20 0.49
HPGD P15428 2/20 0.49
CASP1 P29466 2/20 0.49
CASP7 P55210 2/20 0.49
KMT2A Q03164 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
USP2 O75604 1/20 0.49
THRB P10828 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
ALOX12 P18054 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8575384 1.00 DPP4 (0.61) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL769311 0.98 DPP4 (0.64) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL22763311 0.98 DPP4 (0.64) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL8573710 0.98 DPP4 (0.64) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL19721713 0.88 DPP4 (0.69) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL30375911 0.88 DPP4 (0.69) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL12307005 0.84 DPP4 (0.36) DPP4ALDH1A1KDM4EMAPTKMT2A
SCHEMBL22734798 0.82 DPP4 (0.43) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL8010720 0.82 DPP4 (0.43) DPP4ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL20371369 0.82 DPP4 (0.57) DPP4ALDH1A1KDM4EGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 US disclosed
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF UNIV MICHIGAN TECH (US) 2017-01-19 US disclosed
US-9412949-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2016-08-09 US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 US disclosed
US-5753692-A PLANT EXTRACTS, IMMUNOSTIMULANTS TREATING IMMUNODEFICIENCY DISEASES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-19 US disclosed
US-5747525-A ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-05 US disclosed
US-5602170-A ADMINISTERING ANTIIFLAMMATORY AGENT INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1997-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 DPP4 916/4885ALDH1A1 2651/4885KDM4E 4075/4885
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 DPP4 916/4885ALDH1A1 2651/4885KDM4E 4075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.