Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | XPO1 | O14980 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922851 | 0.92 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1PLA2G4AMEN1PTGES | |
| SCHEMBL21812554 | 0.86 | CYSLTR1 (0.66) | CYSLTR2CYSLTR1PLA2G4AMEN1PTGES | |
| SCHEMBL10882149 | 0.85 | CYSLTR1 (0.57) | CYSLTR2CYSLTR1PLA2G4AMEN1PTGES | |
| SCHEMBL14860952 | 0.84 | CYSLTR1 (0.63) | CYSLTR2CYSLTR1PLA2G4AMEN1PTGES | |
| N-Dealkylated Derivative SCHEMBL14862820 | 0.81 | CYSLTR2 (0.83) | CYSLTR2CYSLTR1PLA2G4AMEN1PTGES | |
| SCHEMBL4773609 | 0.80 | — | — | |
| SCHEMBL14862821 | 0.79 | CYSLTR1 (0.64) | CYSLTR2CYSLTR1PLA2G4AMEN1PTGES | |
| SCHEMBL8951644 | 0.79 | CYSLTR1 (0.71) | CYSLTR2CYSLTR1PLA2G4AMEN1PTGES | |
| SCHEMBL4773611 | 0.73 | — | — | |
| SCHEMBL22768779 | 0.73 | EPHX2 (0.70) | CYSLTR1EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002038545-A2 | CRYSTALLINE ETHANOLATE SOLVATE FORM OF ZAFIRLUKAST, PROCESS FOR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS THEREOF | FINETECH LABORATORIES LTD. (IL) | 2002-05-16 | — | — | WO | disclosed |