SCHEMBL7693302

SCHEMBL7693302

Cc1ccc(CN2Cc3ccccc3C[C@H](NCc3cncn3Cc3ccc(C#N)cc3)C2)cc1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.60
FNTB P49356 20/20 0.60
PGGT1B P53609 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7693304 1.00 FNTA (0.60) FNTAFNTBPGGT1B
SCHEMBL7698995 0.94 FNTA (0.67) FNTAFNTBPGGT1B
SCHEMBL7698998 0.94 FNTA (0.67) FNTAFNTBPGGT1B
SCHEMBL7697314 0.91 FNTA (0.70) FNTAFNTBPGGT1B
SCHEMBL7697317 0.91 FNTA (0.70) FNTAFNTBPGGT1B
SCHEMBL7696236 0.90 FNTA (0.59) FNTAFNTBPGGT1B
SCHEMBL7696232 0.90 FNTA (0.59) FNTAFNTBPGGT1B
SCHEMBL7692896 0.88 FNTA (0.70) FNTAFNTBPGGT1B
SCHEMBL7692892 0.88 FNTA (0.70) FNTAFNTBPGGT1B
SCHEMBL7699336 0.88 FNTA (0.69) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002057257-A1 CYCLO`C!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREFOR LES LABORATOIRES SERVIER (FR) 2002-07-25 WO disclosed