Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 6/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13940133 | 0.84 | MAPT (0.72) | MAPTTLR7ADORA2AADORA1KMT2A | |
| SCHEMBL10133723 | 0.83 | MAPT (0.68) | MAPTTLR7ADORA2AADORA1KMT2A | |
| SCHEMBL9999685 | 0.80 | MAPT (0.64) | MAPTTLR7ADORA2AADORA1KMT2A | |
| SCHEMBL13602573 | 0.77 | MAPT (0.63) | MAPTTLR7ADORA2AADORA1KMT2A | |
| SCHEMBL11934977 | 0.77 | MAPT (0.60) | MAPTTLR7ADORA2AADORA1KMT2A | |
| SCHEMBL18499105 | 0.76 | CYP2C9 (0.63) | MAPTTLR7ADORA2AADORA1KMT2A | |
| SCHEMBL22275078 | 0.74 | IGF1R (0.63) | MAPTKMT2AIGF1RGAANPSR1 | |
| SCHEMBL7614346 | 0.74 | MAPT (0.57) | MAPTTLR7ADORA2AADORA1KMT2A | |
| SCHEMBL13633918 | 0.74 | MAPT (0.71) | MAPTKMT2AMAPK1GAAMEN1 | |
| SCHEMBL10073642 | 0.74 | MAPT (0.63) | MAPTTLR7KMT2AIGF1RADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062755-A2 | POLYAMIDE ANALOGS AS DNA MINOR GROOVE BINDERS | GENELABS TECHNOLOGIES, INC. (US) | 2002-08-15 | — | — | WO | claimed |
| WO-2002062755-A2 | POLYAMIDE ANALOGS AS DNA MINOR GROOVE BINDERS | GENELABS TECHNOLOGIES, INC. (US) | 2002-08-15 | — | — | WO | disclosed |