Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641409 | 0.88 | PDE10A (0.76) | PDE10A | |
| SCHEMBL9985802 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2634226 | 0.88 | PDE10A (0.76) | PDE10A | |
| SCHEMBL7700929 | 0.88 | PDE10A (0.76) | PDE10A | |
| SCHEMBL9985799 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL12030795 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7706430 | 0.87 | PDE10A (0.73) | PDE10A | |
| SCHEMBL7695028 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL9985130 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL9985133 | 0.84 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143366-A1 | HETEROARYLOXYCARBOCYCLYL COMPOUNDS AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | disclosed |