Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | DDO | Q99489 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28235813 | 0.92 | KDM4E (0.50) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| SCHEMBL186718 | 0.88 | DAO (0.57) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| SCHEMBL29415610 | 0.88 | DAO (0.57) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| SCHEMBL27660600 | 0.86 | DAO (0.55) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| Methane SCHEMBL28880843 | 0.86 | DAO (0.55) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9638778 | 0.86 | AOC3 (0.56) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL29788370 | 0.86 | AOC3 (0.56) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| Fluoride SCHEMBL27618960 | 0.86 | DAO (0.55) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| SCHEMBL28096830 | 0.84 | DAO (0.53) | LOXL2AOC3KDM4EALDH1A1MAPT | |
| Pyrrole SCHEMBL28184710 | 0.82 | DAO (0.48) | LOXL2AOC3KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413962-B1 | ANESTHESIA AND TEMPERATURES REDUCTION; ALPHA-ADRENOCEPTOR AGONIST; RESTORATIVE TO CENTRAL NERVOUS SYSTEM, ESPECIALLY MOTOR AND SENSORY FUNCTIONAL LOSSES FROM TRAMATIC SPINAL CORD INJURIES; ANTISPASTICS; NONSEDATIVE; SIDE EFFECT REDUCTION | NAFTCHI N ERIC (US) | 2002-07-02 | — | — | US | disclosed |