Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.56 |
| ▸ | OTC | P00480 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 6/20 | 0.45 |
| ▸ | NOS3 | P29474 | 5/20 | 0.45 |
| ▸ | NOS1 | P29475 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL4000670 | 1.00 | GSR (0.56) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL23235587 | 1.00 | GSR (0.56) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL769419 | 1.00 | GSR (0.56) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL27500414 | 0.98 | GSR (0.55) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL27622618 | 0.98 | GSR (0.55) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL10955828 | 0.97 | GSR (0.62) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL517577 | 0.97 | GSR (0.62) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL1227757 | 0.97 | GSR (0.61) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL25278795 | 0.97 | GSR (0.61) | GSROTCDDAH1NOS2NOS3 | |
| Arginine SCHEMBL18205261 | 0.95 | GSR (0.51) | GSROTCDDAH1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948775-B1 | COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA | US HEALTH (US) | 2018-10-03 | — | — | EP | claimed |
| US-20150344969-A1 | COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES | 2015-12-03 | — | — | US | claimed |
| EP-2948775-A2 | COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA | The United States Of America,As Represented By The Secretary, Department Of Health & Human Services (US) | 2015-12-02 | — | — | EP | claimed |
| WO-2014116833-A2 | COMPOSITIONS AND METHODS FOR DETECTING NEOPLASIA | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2014-07-31 | — | — | WO | claimed |
| EP-0507872-B1 | THE USE OF ARGININE AS AN IMMUNOSTIMULATOR | BRAUN MEDICAL INC (US) | 2000-04-26 | — | — | EP | claimed |
| WO-2026107124-A1 | GRAPH NEURAL NETWORK-BASED SYSTEM FOR METABOLOMIC NETWORK ANALYSIS AND EMBRYO IMPLANTATION PREDICTION | RHEA FERTILITY SINGAPORE PTE. LTD. (SG) | 2026-05-21 | — | — | WO | disclosed |
| US-20240180976-A1 | MICROBIAL CONSORTIUM AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-06-06 | — | — | US | disclosed |
| US-20210315947-A1 | MICROBIAL CONSORTIUM AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-10-14 | — | — | US | disclosed |
| US-20210253702-A1 | MULTI-SPECIFIC ANTIBODY CONSTRUCTS | BIOATLA, INC. (US) | 2021-08-19 | — | — | US | disclosed |
| US-11033588-B2 | Compositions for treating inflammation and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-15 | — | — | US | disclosed |
| EP-3807318-A1 | MULTI-SPECIFIC ANTIBODY CONSTRUCTS | Bioatla, Inc. (US) | 2021-04-21 | — | — | EP | disclosed |
| CN-112513081-A | Multispecific antibody constructs | 生物蛋白有限公司 | 2021-03-16 | — | — | CN | disclosed |
| US-4376825-A | ENZYME-BOUND LIGANDS WITH FREE REACTIVE SITES WHICH CAN BIND RECEPTORS | SYVA COMPANY (US) | 1983-03-15 | — | — | US | disclosed |
| US-4282325-A | FOR AMPLIFICATION IN ASSAYS | SYVA COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4203802-A | ENZYME BOUND TO AN ESTROGEN LIGAND | SYVA COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4190496-A | RECEPTOR, LIGAND, AND ENZYME-BOUND | SYVA COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4069214-A | ACRYLIC ESTER POLYMER, AMINO ACID CURING AGENT, COATING METALS, BONDING PLYWOOD, FINISHING TEXTILES | SANYO TRADING CO., LTD. (JA) | 1978-01-17 | — | — | US | disclosed |
| US-4067774-A | Compounds for enzyme amplification assay | SYVA COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-3975237-A | LIGANDS | SYVA COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3966556-A | Compounds for enzyme amplification assay methadone analogs | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |