Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.46 |
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122416 | 1.00 | ADRB3 (0.46) | ADRB3BACE1KDM4EALDH1A1TAAR1 | |
| SCHEMBL7122412 | 1.00 | ADRB3 (0.46) | ADRB3BACE1KDM4EALDH1A1TAAR1 | |
| SCHEMBL7122414 | 0.95 | BACE1 (0.44) | ADRB3BACE1KDM4EALDH1A1TAAR1 | |
| SCHEMBL27635276 | 0.90 | GLI1 (0.46) | ADRB3BACE1KDM4EALDH1A1TAAR1 | |
| SCHEMBL19245779 | 0.90 | TAAR1 (0.46) | ADRB3BACE1KDM4EALDH1A1TAAR1 | |
| SCHEMBL12834438 | 0.89 | BACE1 (0.44) | ADRB3BACE1KDM4EALDH1A1TAAR1 | |
| SCHEMBL7120686 | 0.87 | ADRB3 (0.43) | ADRB3BACE1 | |
| SCHEMBL7993383 | 0.87 | CYP51A1 (0.46) | ADRB3BACE1 | |
| SCHEMBL7120679 | 0.87 | ADRB3 (0.43) | ADRB3BACE1 | |
| SCHEMBL17177098 | 0.85 | KCNH2 (0.45) | BACE1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |
| WO-2002006258-A1 | AZOLIDINES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |