Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540875 | 0.89 | PPARA (0.39) | PPARAPPARGCXCR2 | |
| SCHEMBL6540867 | 0.89 | PPARA (0.39) | PPARAPPARGCXCR2 | |
| SCHEMBL6487557 | 0.85 | SPHK1 (0.39) | NR1H2NR1H3SPHK1PPARGBRD4 | |
| SCHEMBL6487562 | 0.85 | SPHK1 (0.39) | NR1H2NR1H3SPHK1PPARGBRD4 | |
| SCHEMBL2288435 | 0.85 | SPHK1 (0.39) | NR1H2NR1H3SPHK1PPARGBRD4 | |
| SCHEMBL2290598 | 0.83 | SPHK1 (0.43) | NR1H2NR1H3SPHK1BRD4GPR119 | |
| SCHEMBL2290590 | 0.83 | SPHK1 (0.43) | NR1H2NR1H3SPHK1BRD4GPR119 | |
| SCHEMBL19331727 | 0.82 | SPHK1 (0.37) | NR1H2NR1H3SPHK1BRD4CXCR2 | |
| SCHEMBL19331731 | 0.82 | SPHK1 (0.37) | NR1H2NR1H3SPHK1BRD4CXCR2 | |
| SCHEMBL2291830 | 0.82 | SMN1; SMN2 (0.40) | SPHK1BRD4HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |