Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11628355 | 0.98 | TSHR (0.48) | TSHRALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL14400889 | 0.91 | PPM1B (0.43) | ALDH1A1PPM1BPTPN1PPP1CCMAPT | |
| SCHEMBL4521342 | 0.91 | PPM1B (0.43) | ALDH1A1PPM1BPTPN1PPP1CCMAPT | |
| SCHEMBL9083280 | 0.91 | PPM1B (0.43) | ALDH1A1PPM1BPTPN1PPP1CCMAPT | |
| SCHEMBL14393314 | 0.91 | PPM1B (0.43) | ALDH1A1PPM1BPTPN1PPP1CCMAPT | |
| SCHEMBL9083292 | 0.91 | PPM1B (0.43) | ALDH1A1PPM1BPTPN1PPP1CCMAPT | |
| SCHEMBL4415431 | 0.91 | PPM1B (0.43) | ALDH1A1PPM1BPTPN1PPP1CCMAPT | |
| Hydrochloric Acid SCHEMBL4415434 | 0.89 | PPM1B (0.42) | TSHRALDH1A1PPM1BPTPN1PPP1CC | |
| Hydrochloric Acid SCHEMBL4415435 | 0.89 | PPM1B (0.42) | TSHRALDH1A1PPM1BPTPN1PPP1CC | |
| Hydrochloric Acid SCHEMBL4415429 | 0.89 | PPM1B (0.42) | TSHRALDH1A1PPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346547-B1 | TREATING ATHEROSCLEROSIS, RESTENOSIS AND STROKE | CHECKPOINT, GENETICS, INC. | 2002-02-12 | — | — | US | disclosed |
| EP-1153010-A1 | $i(N)-SUBSTITUTED AMINO ACIDS, ANTIOXIDANT PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS USING SAME | Checkpoint Genetics, Inc. (US) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000046183-A1 | N-SUBSTITUTED AMINO ACIDS, ANTIOXIDANT PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS USING SAME | CHECKPOINT GENETICS, INC. (US) | 2000-08-10 | — | — | WO | disclosed |