SCHEMBL7695791

SCHEMBL7695791

CCCOc1c(OCc2ccccc2)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CCC

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7133900 1.00 PTAFR (0.77) PTAFR
SCHEMBL7594055 1.00 PTAFR (0.77) PTAFR
SCHEMBL10429013 0.95 PTAFR (0.69) PTAFR
SCHEMBL9691535 0.94 PTAFR (0.81) PTAFR
SCHEMBL9691538 0.94 PTAFR (0.81) PTAFR
SCHEMBL9691546 0.94 PTAFR (0.81) PTAFR
SCHEMBL9691932 0.94 PTAFR (0.78) PTAFR
SCHEMBL9691939 0.94 PTAFR (0.78) PTAFR
SCHEMBL9691949 0.94 PTAFR (0.78) PTAFR
SCHEMBL9692429 0.92 PTAFR (0.73) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749306-A4 COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS CYTOMED INC (US) 1997-04-16 EP claimed
EP-0749306-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS CYTOMED, INC. (US) 1996-12-27 EP claimed
US-5463083-A Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders CYTOMED, INC. (US) 1995-10-31 US claimed
WO-1995018610-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS CYTOMED, INC. (US) 1995-07-13 WO claimed
US-6420392-B1 PAF RECEPTOR ANTAGONISTS AND/OR BY INHIBITING THE ENZYME 5-LIPOXYGENASE. MILLENNIUM PHARMACEUTICALS, INC. 2002-07-16 US disclosed
US-5741809-A Compounds and methods for the treatment of cardiovascular inflammatory and immune disorders CYTOMED, INC. (US) 1998-04-21 US disclosed
EP-0749306-A4 COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS CYTOMED INC (US) 1997-04-16 EP disclosed
EP-0749306-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS CYTOMED, INC. (US) 1996-12-27 EP disclosed
US-5463083-A Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders CYTOMED, INC. (US) 1995-10-31 US disclosed
WO-1995018610-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS CYTOMED, INC. (US) 1995-07-13 WO disclosed