Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694128 | 0.93 | MCHR1 (0.42) | MCHR1POLBKDM4EUSP2LMNA | |
| SCHEMBL7697705 | 0.90 | MCHR1 (0.44) | MCHR1HTR2CPDE4APDE4BPDE4C | |
| SCHEMBL7697825 | 0.89 | MCHR1 (0.43) | MCHR1POLBKDM4EUSP2LMNA | |
| SCHEMBL7698418 | 0.88 | PDE4A (0.41) | MCHR1POLBPDE4APDE4BPDE4C | |
| SCHEMBL7692463 | 0.88 | MCHR1 (0.44) | MCHR1HTR2CPDE4APDE4BPDE4C | |
| SCHEMBL7699738 | 0.88 | MCHR1 (0.42) | MCHR1POLBKDM4EUSP2LMNA | |
| SCHEMBL7692409 | 0.84 | MCHR1 (0.44) | MCHR1HTR2CPDE4APDE4BPDE4C | |
| SCHEMBL7700767 | 0.83 | MCHR1 (0.42) | MCHR1HTR2CPDE4APDE4BPDE4C | |
| SCHEMBL7695681 | 0.83 | PDE4A (0.42) | MCHR1LMNAHTR2CPDE4APDE4B | |
| SCHEMBL7696591 | 0.80 | MCHR1 (0.49) | MCHR1LMNAHTR2CPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |