Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.33 |
| ▸ | OAT | P04181 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370115 | 0.87 | CYP1A2 (0.44) | CYP1A2ACMSDKDM4EALDH1A1MAPT | |
| Ethylene Glycol SCHEMBL3016260 | 0.84 | CYP1A2 (0.38) | CYP1A2ACMSDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL251512 | 0.77 | CYP1A2 (0.57) | CYP1A2GFERKDM4EALDH1A1MAPT | |
| SCHEMBL87519 | 0.77 | CYP1A2 (0.57) | CYP1A2GFERACMSDKDM4EALDH1A1 | |
| SCHEMBL3091854 | 0.75 | CYP1A2 (0.55) | CYP1A2GFERKDM4EALDH1A1MAPT | |
| Cyclohexane SCHEMBL1538047 | 0.75 | CYP1A2 (0.55) | CYP1A2GFERKDM4EALDH1A1MAPT | |
| SCHEMBL2034342 | 0.75 | CYP1A2 (0.55) | CYP1A2GFERKDM4EALDH1A1MAPT | |
| SCHEMBL250454 | 0.75 | CYP1A2 (0.55) | CYP1A2GFERKDM4EALDH1A1MAPT | |
| SCHEMBL973641 | 0.75 | CYP1A2 (0.55) | CYP1A2GFERKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL195800 | 0.75 | CYP1A2 (0.55) | CYP1A2GFERKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065948-A1 | CO-EXTRUSION OF RHEOLOGICALLY MISMATCHED POLYMERS | Lubrizol Advanced Materials, Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| US-6451887-B1 | Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-17 | — | — | US | disclosed |