Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697385 | 0.89 | PDE4B (0.38) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL7700466 | 0.89 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL7700903 | 0.89 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7698885 | 0.89 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL7698199 | 0.88 | PDE4B (0.42) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL7700388 | 0.87 | PDE4B (0.42) | PDE4APDE4BPDE4CPDE4DRXFP1 | |
| SCHEMBL7698384 | 0.87 | PDE4B (0.39) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7693762 | 0.85 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7691850 | 0.84 | PDE4B (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7692927 | 0.78 | PDE4B (0.44) | PDE4APDE4BPDE4CPDE4DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081446-A1 | 3-CYCLOPENTYLOXY-4-METHOXYPHENYL-ISOINDOLINONE DERIVATIVES AND THE USE THEREOF | DAEWOONG CO., LTD. (KR) | 2002-10-17 | — | — | WO | disclosed |