Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165769 | 0.97 | NPC1 (0.53) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL17656943 | 0.87 | NPC1 (0.61) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL6215142 | 0.85 | NPC1 (0.73) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL973317 | 0.84 | NPC1 (0.68) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL30786723 | 0.84 | NPC1 (0.68) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL28491297 | 0.83 | SMN1; SMN2 (0.47) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL7694544 | 0.83 | NPC1 (0.56) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL7694669 | 0.83 | NPC1 (0.65) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL7696224 | 0.83 | NPC1 (0.72) | NPC1SMN1; SMN2RAB9APDGFRBKDR | |
| SCHEMBL7600391 | 0.82 | TLR9 (0.51) | NPC1SMN1; SMN2RAB9APDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |