Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575141 | 1.00 | PTPN11 (0.40) | PTPN11NPC1RAB9ACYP3A4CYP2D6 | |
| SCHEMBL7702554 | 0.94 | NPC1 (0.41) | PTPN11NPC1RAB9APTPN1PTPN6 | |
| SCHEMBL7702561 | 0.94 | NPC1 (0.41) | PTPN11NPC1RAB9APTPN1PTPN6 | |
| SCHEMBL6867724 | 0.88 | NPC1 (0.45) | PTPN11NPC1RAB9ACYP3A4CYP2D6 | |
| SCHEMBL29637247 | 0.88 | NPC1 (0.45) | PTPN11NPC1RAB9ACYP3A4CYP2D6 | |
| SCHEMBL6867726 | 0.88 | NPC1 (0.45) | PTPN11NPC1RAB9ACYP3A4CYP2D6 | |
| SCHEMBL7698053 | 0.86 | CNR1 (0.42) | PTPN11NPC1RAB9A | |
| SCHEMBL9177994 | 0.84 | NPC1 (0.41) | PTPN11NPC1RAB9APTPN1PTPN6 | |
| SCHEMBL9177988 | 0.84 | NPC1 (0.41) | PTPN11NPC1RAB9APTPN1PTPN6 | |
| SCHEMBL5186121 | 0.83 | PTPN11 (0.41) | PTPN11NPC1RAB9ACYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344505-B1 | Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers | CYTEC INDUSTRIES INC. | 2002-02-05 | — | — | US | disclosed |