Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.46 |
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674210 | 0.89 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL3668758 | 0.89 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL3673010 | 0.89 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL3668642 | 0.89 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL3668594 | 0.89 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL3670562 | 0.86 | HMGCR (0.46) | PTPN7HMGCRRECQLTDP1KDM4E | |
| SCHEMBL99421 | 0.83 | — | — | |
| SCHEMBL3673434 | 0.77 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL3673020 | 0.77 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL3666369 | 0.77 | HMGCR (0.49) | PTPN7HMGCRRECQLTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342149-B1 | REACTION OF CARBON DIOXIDE UNDER PRESSURE WITH ELECTROLYSIS FOR CARBONYLATION | FORSCHUNGSZENTRUM KARLSRUHE (DE) | 2002-01-29 | — | — | US | disclosed |