Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15456616 | 0.79 | CSNK1A1 (0.37) | CSNK1A1CLK4KDRPDE4APDE4B | |
| SCHEMBL1346399 | 0.76 | PDPK1 (0.34) | KDRKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL6311839 | 0.74 | CSNK1A1 (0.43) | CSNK1A1CLK4TP53ADORA2AADORA1 | |
| SCHEMBL9437096 | 0.72 | PI4KA (0.34) | GDAHTTKMT2A | |
| SCHEMBL7697033 | 0.71 | HSD17B10 (0.37) | CSNK1A1CLK4RXFP1ADORA2AADORA1 | |
| SCHEMBL1737266 | 0.68 | DYRK1A (0.34) | NPC1RAB9AKDM4EHTTMEN1 | |
| SCHEMBL6876145 | 0.67 | HRH3 (0.34) | CSNK1A1CLK4PDE4APDE4BPDE4C | |
| SCHEMBL1713206 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL28274257 | 0.66 | HRH3 (0.33) | CSNK1A1CLK4PDE4APDE4BPDE4C | |
| SCHEMBL11666510 | 0.62 | CSNK1A1 (0.50) | CSNK1A1CLK4RXFP1TP53ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| WO-2000042043-A1 | PYRROLO[2,3-d]PYRIMIDINES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-07-20 | — | — | WO | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |