Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PLEKHA1 | Q9HB21 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398813 | 1.00 | RECQL (0.50) | RECQLALOX15KMT2AGAAAKT1 | |
| SCHEMBL7235302 | 0.78 | — | — | |
| SCHEMBL31683749 | 0.65 | — | — | |
| SCHEMBL15499334 | 0.61 | — | — | |
| SCHEMBL7244403 | 0.59 | GAA (0.45) | RECQLALOX15KMT2AGAA | |
| SCHEMBL18597741 | 0.58 | KMT2A (0.33) | RECQLALOX15KMT2AGAA | |
| SCHEMBL17584808 | 0.57 | — | — | |
| SCHEMBL3058905 | 0.56 | HSD17B10 (0.50) | RECQLALOX15KMT2AGAA | |
| SCHEMBL77033 | 0.56 | CYP1A2 (0.34) | RECQLALOX15KMT2A | |
| SCHEMBL91392 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342589-B1 | REACTING 3,6-BIS(3,5-DIMETHYLPYRAZOL-1-YL)-1,2,4,5-TETRAZINE WITH HYDRAZINE; FURTHER REACTING WITH N-BROMOSUCCINIMIDE IN ACETONITRILE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY | 2002-01-29 | — | — | US | disclosed |