Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 17/20 | 0.53 |
| ▸ | RAMP1 | O60894 | 9/20 | 0.53 |
| ▸ | CALCA | P06881 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965881 | 1.00 | CALCRL (0.53) | CALCRLRAMP1CALCAPOLB | |
| SCHEMBL3960149 | 0.91 | CALCRL (0.57) | CALCRLRAMP1CALCAPOLB | |
| SCHEMBL3967296 | 0.86 | CALCRL (0.55) | CALCRLRAMP1CALCA | |
| SCHEMBL3956564 | 0.82 | CALCRL (0.60) | CALCRLRAMP1CALCA | |
| SCHEMBL3965111 | 0.81 | CALCRL (0.62) | CALCRLRAMP1CALCA | |
| SCHEMBL3965048 | 0.81 | CALCRL (0.55) | CALCRLRAMP1CALCA | |
| SCHEMBL3967290 | 0.78 | CALCRL (0.60) | CALCRLRAMP1CALCA | |
| SCHEMBL3954332 | 0.78 | CALCRL (0.82) | CALCRLRAMP1CALCA | |
| SCHEMBL3954327 | 0.78 | CALCRL (0.60) | CALCRLRAMP1CALCA | |
| SCHEMBL3959858 | 0.78 | CALCRL (0.53) | CALCRLRAMP1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344449-B1 | HEADACHE AND MORPHINE DEPENDENCE | DR. KARL THOMAE GMBH (DE) | 2002-02-05 | — | — | US | disclosed |