Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.56 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 3/20 | 0.51 |
| ▸ | KIT | P10721 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691122 | 0.84 | MAPK14 (0.50) | MAPK14DDR2LMNASMN1; SMN2MAPT | |
| SCHEMBL7694596 | 0.83 | MAPK14 (0.56) | MAPK14DDR2ABL1KITMAPK13 | |
| SCHEMBL7694545 | 0.74 | MAPK14 (0.48) | MAPK14DDR2LMNASMN1; SMN2ABL1 | |
| SCHEMBL12245428 | 0.72 | MAPK14 (1.00) | MAPK14DDR2ABL1KITMAPK13 | |
| SCHEMBL3259418 | 0.72 | MAPK14 (0.53) | MAPK14DDR2ABL1KITMAPK9 | |
| SCHEMBL12245436 | 0.72 | MAPK14 (1.00) | MAPK14DDR2ABL1KITMAPK13 | |
| SCHEMBL12245435 | 0.72 | MAPK14 (1.00) | MAPK14DDR2ABL1KITMAPK13 | |
| SCHEMBL3260008 | 0.71 | ABL1 (0.52) | MAPK14DDR2ABL1KITHTT | |
| SCHEMBL3171750 | 0.71 | MAPK14 (0.58) | MAPK14DDR2LMNASMN1; SMN2ABL1 | |
| SCHEMBL5732947 | 0.70 | MAPK14 (1.00) | MAPK14DDR2ABL1MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |