Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699574 | 1.00 | TACR1 (0.38) | TACR1TACR2TACR3 | |
| SCHEMBL7547907 | 0.90 | TACR1 (0.38) | TACR1 | |
| SCHEMBL7699507 | 0.90 | TACR1 (0.38) | TACR1 | |
| SCHEMBL6616720 | 0.90 | TACR1 (0.40) | TACR1 | |
| SCHEMBL6616383 | 0.90 | TACR1 (0.40) | TACR1 | |
| SCHEMBL6616716 | 0.90 | TACR1 (0.40) | TACR1 | |
| SCHEMBL7475176 | 0.87 | TACR1 (0.49) | TACR1 | |
| SCHEMBL7475181 | 0.87 | TACR1 (0.49) | TACR1 | |
| SCHEMBL7487946 | 0.87 | TACR1 (0.49) | TACR1 | |
| SCHEMBL6615413 | 0.80 | TACR1 (0.39) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016344-A1 | TETRAHYDROPYRAN DERIVATIVES AS NK-1 RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 2002-02-28 | — | — | WO | claimed |
| WO-2002016344-A1 | TETRAHYDROPYRAN DERIVATIVES AS NK-1 RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 2002-02-28 | — | — | WO | disclosed |