SCHEMBL7699591

SCHEMBL7699591

CCOC(=O)c1nc(-c2ccccc2)oc1-c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 7/20 0.62
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
HPGD P15428 1/20 0.57
HSD17B10 Q99714 1/20 0.57
GAA P10253 1/20 0.52
RAB9A P51151 1/20 0.52
PDCD4 Q53EL6 1/20 0.49
AR P10275 3/20 0.48
MAPT P10636 2/20 0.48
CACNA1D Q01668 1/20 0.46
ELANE P08246 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29158611 1.00 TARBP2 (0.62) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL7699412 0.92 TARBP2 (0.52) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL29158730 0.90 TARBP2 (0.51) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL29158661 0.89 TARBP2 (0.65) TARBP2ALDH1A1GAARAB9APDCD4
SCHEMBL27189076 0.88 TARBP2 (0.78) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL7695426 0.88 GAA (0.49) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL4499055 0.88 TARBP2 (0.73) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL29158639 0.87 GAA (0.48) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL29158785 0.87 TARBP2 (0.52) TARBP2KMT2AKDM4EALDH1A1HPGD
SCHEMBL29158993 0.84 TARBP2 (0.61) TARBP2KMT2AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002064558-A2 OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS SANKYO COMPANY, LIMITED (JP) 2002-08-22 WO disclosed