Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.85 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.85 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095234 | 1.00 | ADRB3 (0.85) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7094547 | 0.92 | ADRB3 (1.00) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7091469 | 0.91 | ADRB3 (0.79) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7096881 | 0.88 | ADRB3 (0.91) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7587081 | 0.88 | ADRB3 (0.91) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7594822 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7235833 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7090768 | 0.87 | ADRB3 (0.79) | ADRB3ADRB1ADRB2KDM4EMEN1 | |
| SCHEMBL7096112 | 0.86 | ADRB3 (0.85) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7164357 | 0.86 | ADRB3 (0.85) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006229-A2 | HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |